Yellow nail syndrome. Possible association with malignancy

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Abstract
A dramatic resolution of yellow nail deformity occurred in a 66 yr old man shortly after removal of a carcinoma of the larynx. A productive cough developed 17 mo. later, and radiologic evidence of bronchiectasis was found. There was no evidence of lymphedema, pleural effusion, sinusitis or immunologic abnormalities. At least 3 other patients with a variant of yellow nail syndrome died of malignancy. The resolution of the nail deformity following laryngectomy may not be fortuitous.

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