Urinary 5-hydroxyindoleacetic acid in 8-hour collections as an aid in diagnosis of coeliac disease.
Open Access
- 1 October 1975
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 50 (10) , 779-781
- https://doi.org/10.1136/adc.50.10.779
Abstract
8-hour urine excretions of 5-hydroxyindoleacetic acid (5-HIAA) were measured in 18 children with coeliac disease before treatment and the results expressed as microgram 5-HIAA/mg creatinine. Similar measurements were made on urine collections from an age-matched control group of 24 children. Significantly higher values of 5-HIAA excretion were found in children with untreated coeliac disease. Measurement of the 5-HIAA: creatinine ratio in 8-hour urine collections is therefore proposed as an aid in the diagnosis of coeliac disease.Keywords
This publication has 3 references indexed in Scilit:
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- A New Modification for the Determination of 5- Ydroxy-Indole-Acetic Acid (5HIAA) in Urine Unspecific Nitrosonaphthol Reactions and Their EliminationScandinavian Journal of Clinical and Laboratory Investigation, 1964
- Endocrine Aspects of ArgentaffinomaScottish Medical Journal, 1956