Methylmercury: Decreased Antibody Formation in Mice

Abstract
Antibody synthesis was decreased in mice fed 1, 5 or 10 ppm methylmercury for 10 wk. The primary immune response was significantly suppressed, while the secondary response was impaired but not significantly. Methylmercury apparently affects the B [bone marrow-derived] cell or plasma-cell synthesis of Ig[immunoglobulin]M antibody.

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