RELATIONSHIP OF LESION SIZE TO SURVIVAL IN PATIENTS WITH STAGE-IB SQUAMOUS-CELL CARCINOMA OF THE CERVIX UTERI TREATED BY RADIATION-THERAPY

  • 1 January 1980
    • journal article
    • research article
    • Vol. 150  (4) , 529-531
Abstract
Patients (45) with stage IB squamous cell carcinoma of the cervix uteri were treated with radiation therapy alone. The 5 yr actuarial survival rate of the 22 patients in group 1 in whom the tumor was < 4 cm in diameter was 95%, significantly higher than the 67% survival rate in the 23 patients in group 2 with bulky lesions .gtoreq. 4 cm in diameter, P < 0.05. These results of radiation therapy are consistent with surgical results recently reported and indicate that patients with bulky lesions, especially those tumors .gtoreq. 4 cm in size, comprise a high risk subset within the stage IB classification. A new classification is proposed in which bulky lesions are designated stage IC, advanced overt, so that such high risk patients might be identified and more efficacious treatment regimens might be developed.

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