17α-Alkyl- or 17α-substituted benzyl-17β-estradiols: A new family of estrone-sulfatase inhibitors
- 21 July 1998
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 8 (14) , 1891-1896
- https://doi.org/10.1016/s0960-894x(98)00330-8
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Pharmacokinetics of oestrone-3-O-sulphamateThe Journal of Steroid Biochemistry and Molecular Biology, 1996
- Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patientsJournal of Clinical Endocrinology & Metabolism, 1996
- The development of steroid sulphatase inhibitorsEndocrine-Related Cancer, 1996
- Heteroatom-substituted analogues of the active-site directed inhibitor estra-1,3,5(10)-trien-17-one-3-sulphamate inhibit estrone sulphatase by a different mechanismThe Journal of Steroid Biochemistry and Molecular Biology, 1996
- Estrone sulfate-sulfatase and 17β-hydroxysteroid dehydrogenase activities: a hypothesis for their role in the evolution of human breast cancer from hormone-dependence to hormone-independenceThe Journal of Steroid Biochemistry and Molecular Biology, 1995
- Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potentialJournal of Medicinal Chemistry, 1994
- IntracrinologyMolecular and Cellular Endocrinology, 1991
- Estrogenic Regulation of Growth and Polypeptide Growth Factor Secretion in Human Breast CarcinomaEndocrine Reviews, 1987
- Enzymatic Control of Estrogen Production in Human Breast Cancer: Relative Significance of Aromatase versus Sulfatase PathwaysAnnals of the New York Academy of Sciences, 1986
- The plasma concentration of oestrone sulphate in postmenopausal women: Lack of diurnal variation, effect of ovariectomy, age and weightJournal of Steroid Biochemistry, 1981