Reactive hyperaemia in the dog heart: inter-relations between adenosine, ATP, and aminophylline and the effect of indomethacin
- 1 March 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 11 (2) , 113-121
- https://doi.org/10.1093/cvr/11.2.113
Abstract
Intracoronary adenosine, ATP, and the release of an 8 second occlusion increased coronary blood flow (CBF) to a similar extent. Aminophylline decreased the CBF response to adenosine by 80% and that to an 8 s occlusion by 20% but did not change the CBF response to ATP. Indomethacin had no effect on CBF. The results suggest that the increase in CBF after brief occlusions is not mediated in a major way by adenosine or prostaglandins.This publication has 0 references indexed in Scilit: