A FACILE SYNTHESIS OF γ,δ-UNSATURATED ESTERS BY THE Pd(II) CATALYZED CLAISEN REARRANGEMENT
- 5 September 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 13 (9) , 1535-1536
- https://doi.org/10.1246/cl.1984.1535
Abstract
A mixed ortho ester is prepared under mild conditions from an allyl alcohol and a ketene acetal in the presence of PdCl2(COD). The ortho ester thus formed is successively treated with a catalytic amount of PdCl2(PPh3)2 in refluxing p-xylene to afford a γ,δ-unsaturated ester in a high yield under neutral conditions.Keywords
This publication has 1 reference indexed in Scilit:
- Simple stereoselective version of the Claisen rearrangement leading to trans-trisubstituted olefinic bonds. Synthesis of squaleneJournal of the American Chemical Society, 1970