Ionophore-mediated Ca2+ countertransport: role of Na+, Li+ or H+ gradient
- 1 April 1980
- journal article
- research article
- Published by Springer Nature in Molecular and Cellular Biochemistry
- Vol. 30 (2) , 67-70
- https://doi.org/10.1007/bf00227919
Abstract
Summary In an artificial system, the ionophore A23187, which transports Ca2+ but not Na+, is able to mediate the uphill translocation of Ca2+ from one aqueous medium to another across an organic immiscible phase, provided that a Na+, Li+ or H+ gradient is imposed on the system. Therefore, in the process known as Na-Ca countertransport, the downhill influx of Na+ may not be necessary for causing Ca2+ extrusion against its electrochemical gradient.Keywords
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- The interrelationship between sodium and calcium fluxes across cell membranesPublished by Springer Nature ,1973
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