Down???s Syndrome and the Gastrointestinal Tract
- 1 April 1986
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Clinical Gastroenterology
- Vol. 8 (2) , 111-114
- https://doi.org/10.1097/00004836-198604000-00002
Abstract
Gastrointestinal (GI) abnormalities are frequent in patients with Down’s syndrome. In a 12-year retrospective review, we identified 187 patients with Down’s syndrome admitted to the Columbia-Presbyterian Medical Center. Twenty-seven had major GI disorders, the most common being duodenal stenosis (DS, nine), gastroesophageal reflux (GER, five), imperforate anus (five), and Hirschsprung’s disease (four). The mortality for the whole group was 11% (20 patients). The mortality in the small group of patients with duodenal stenosis was particularly high (five out of nine, or 56%). Associated congenital heart disease, especially endocardial cushion defects, and the frequent occurrence of pneumonia contributed to this high mortality rate.Keywords
This publication has 0 references indexed in Scilit: