Relative Importance of Bacteremia and Viremia in the Course of Acute Fevers of Unknown Origin in Outpatient Children

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Abstract
During 12 mo. 80 children > 3 mo. of age seen at an emergency room with acute fevers .gtoreq. 39.7.degree. C (103.5.degree. F) and no localizing signs of infection were studied using blood and buffy coat cultures to isolate bacteria and viruses. Bacteremia was identified in 3 children (3.8%) (2 with Streptococcus pneumoniae and 1 with Neisseria meningitidis). Two children with viremia were identified (both isolates were echo-virus, types 11 and 21, respectively). Of the study children, 58 (72%) were seen again in 24-48 h and 27/58 (46%) were afebrile and completely well. No differences in sex, age or initial white blood cell count existed among those children who returned afebrile and well and those with either localized disease or those persistently febrile.

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