Carbohydrate‐Deficient Transferrin in Alcohol and Nonalcohol Abusers with Liver Disease
- 1 December 1995
- journal article
- Published by Wiley in Alcohol, Clinical and Experimental Research
- Vol. 19 (6) , 1525-1527
- https://doi.org/10.1111/j.1530-0277.1995.tb01018.x
Abstract
Carbohydrate‐deficient transferrin (CDT) has been demonstrated to be a marker of prolonged heavy alcohol consumption. We compared this marker with γ‐glutamyltranspeptidase (GGT) and mean corpuscular volume (MCV) in alcohol and nonalcohol abusers with liver disease. Our results confirm that the sensitivity of CDT in alcoholics is high, although lower than that of GGT and MCV; however, the specificity of CDT was higher than that of the other two markers. This finding supports the notion that CDT is only partially influenced by the presence of liver damage, whereas increases of GGT and MCV are greatly affected by several factors, including liver damage and drugs. Moreover, we observed that the sensitivity and the specificity of CDT were greater than those of GGT and MCV in younger drinkers.Keywords
This publication has 15 references indexed in Scilit:
- Carbohydrate‐Deficient Transferrin (CDT) in Serum as a Possible Indicator of Heavy Drinking in Young University StudentsAlcohol, Clinical and Experimental Research, 1992
- Evaluation of Carbohydrate‐deficient Transferrin Compared with Tf Index and Other Markers of Alcohol AbuseAlcohol, Clinical and Experimental Research, 1989
- Characteristics of Laboratory Markers in Alcohol-Related Organ DamageScandinavian Journal of Gastroenterology, 1989
- Changes in Carbohydrate‐Deficient Transferrin Levels after Alcohol WithdrawalAlcohol, Clinical and Experimental Research, 1988
- Comparison between Different Methods of Detecting Patients with Excessive Consumption of AlcoholActa Medica Scandinavica, 1988
- Carbohydrate‐Deficient Transferrin in Serum in Patients with Liver DiseasesAlcohol, Clinical and Experimental Research, 1987
- Micro Anion Exchange Chromatography of Carbohydrate‐Deficient Transferrin in Serum in Relation to Alcohol Consumption (Swedish Patent8400587–5)Alcohol, Clinical and Experimental Research, 1986
- Biochemical markers of chronic alcoholismAlcohol, 1985
- MEAN CELL VOLUME AND GAMMA-GLUTAMYL-TRANSPEPTIDASE AS MARKERS OF DRINKING IN WORKING MENThe Lancet, 1981
- GAMMA-GLUTAMYL TRANSPEPTIDASE IN CHRONIC ALCOHOLISMThe Lancet, 1970