Niacin Deficiency in the Rhesus Monkey

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Abstract
Rhesus monkeys receiving a niacin-deficient, purified diet containing 9% casein lose weight and develop lowered hemoglobin values after periods of several months. Tryptophan has been shown capable of replacing the dietary niacin required by monkeys. A very inefficient conversion of tryptophan to niacin, however, occurs in this species. The niacin requirements of monkeys receiving various diets are discussed.