Enterococcus faecalis colonisation and endocarditis in five intensive care patients as late sequelae of selective decontamination

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Abstract
To describeEnterococcus faecalis colonisation and endocarditis in 5 intensive care patients after treatment with selective decontamination (SDD). Intensive care unit (ICU) in a general hospital. The patients were admitted to the ICU because of adult respiratory distress syndrome, polytrauma (2 patients), abdominal aortic surgery and gastrointestinal surgery. Because these patients needed mechanical ventilation they received systemic cefotaxime and SDD (polymyxin E, amphotericin B and norfloxacin). Colonisation withE. faecalis was documented in all patients. Intravascular catheter-related infection withE. faecalis occurred in 4 patients. None of the patients received antibiotics active against,E. faecalis, because body temperature normalised after catheter removal. In the course of his ICU stay one patient died. Autopsy showedE. faecalis endocarditis. The other 4 patients recovered from their primary illness, but had to be readmitted after several months because ofE. faecalis endocarditis. One of these patients died. One patient recovered of endocarditis, but one year later valve surgery was necessary. The other 2 patients needed acute valve replacement. The latter 3 patients survived. We observed 5 patients withE. faecalis endocarditis as a late and severe sequela of SDD during their ICU stay.