A CASE OF PORENCEPHALIC DEFECT ASSOCIATED WITH TUBERCULOUS ENCEPHALITIS

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Abstract
Porencephalus was first so termed by Heschl,1in 1859, in his description of brain defects characterized by cavity formations. There still exists considerable doubt as to the primary lesion or cause of these defects, which are often represented by large areas or spaces in the cerebral substance filled with cerebrospinal fluid and covered by pia mater. Heschl, who drew his deductions from gross anatomic studies, considered the loss of brain substance to be due to faulty development from an intra-uterine injury to the anlages of the brain parts. Later,2he admitted the possibility that regressive vascular changes, and perhaps also syphilis, are instrumental in producing the defect. Strümpell3held that it was due to some type of encephalitis of the gray matter, probably analgous to anterior poliomyelitis, a view supported by Schultze4; and Limbeck5published a study of four cases that tended to support the

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