1,3‐Diacyl derivatives of imidazolidine and hexahydropyrimidine: II. Antimycotic activity

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Abstract
Series of 1,3‐diacylated derivatives of imidazolidine and hexahydropyrimidine have been screened for antimycotic activity. Optimum activity was found for the 1,3‐dihexanoyl derivatives in the imidazolidine series, with the higher and lower derivatives being much less active. In the hexahydropyrimidine series the 1,3‐dipentanoyl, ‐dihexanoyl,‐diheptanoyl and ‐dioctanoyl derivatives all exhibited a high degree of inhibition against all four of the test organisms. The latter wereTrichophyton rubrum, T violaceum, Microsporum gypseum andAspergillus flavus.