NIH Plans Study of Diabetes Control and Complications

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To the Editor: The National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases has initiated a multicenter clinical trial — the Diabetes Control and Complications Trial (DCCT) — to address the issue of the relation between metabolic control and chronic complications of diabetes mellitus. The study was undertaken after extensive consultation with diabetes specialists and after determination that a study of this issue is desirable, ethical, and feasible. The trial will consist of four sequential phases: planning, feasibility study, full-scale clinical trial, and data analysis/reporting.A draft protocol for the feasibility study (Phase II) has been developed by . . .

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