Targeting the TGFβ, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma

This publication has 86 references indexed in Scilit:

• FAK Is Required for TGFβ-induced JNK Phosphorylation in Fibroblasts: Implications for Acquisition of a Matrix-remodeling Phenotype
  Molecular Biology of the Cell, 2007
• TGFβ, cardiac fibroblasts, and the fibrotic response
  Cardiovascular Research, 2007
• Betaglycan induces TGF-β signaling in a ligand-independent manner, through activation of the p38 pathway
  Cellular Signalling, 2006
• Constitutive ALK5-Independent c-Jun N-Terminal Kinase Activation Contributes to Endothelin-1 Overexpression in Pulmonary Fibrosis: Evidence of an Autocrine Endothelin Loop Operating through the Endothelin A and B Receptors
  Molecular and Cellular Biology, 2006
• Matrix Contraction by Dermal Fibroblasts Requires Transforming Growth Factor-β/Activin-Linked Kinase 5, Heparan Sulfate-Containing Proteoglycans, and MEK/ERK
  The American Journal of Pathology, 2005
• Novel antisense oligonucleotides targeting TGF-β inhibit in vivo scarring and improve surgical outcome
  Gene Therapy, 2003
• The modular architecture of a new family of growth regulators related to connective tissue growth factor
  Published by Wiley ,2001
• The Loss of Smad3 Results in a Lower Rate of Bone Formation and Osteopenia Through Dysregulation of Osteoblast Differentiation and Apoptosis
  Journal of Bone and Mineral Research, 2001
• Increased endothelin-1 production in fibroblasts derived from patients with systemic sclerosis.
  Annals of the Rheumatic Diseases, 1994
• Accelerated Healing of Incisional Wounds in Rats Induced by Transforming Growth Factor-β
  Science, 1987