Reactivity of α,α-Dihalogenated Imino Compounds. Part VIII1. Aziridine Formation by Lithium Aluminium Hydride Reduction of N-2-(1,1-Dichloroalkylidene) Cyclohexylamines
- 1 January 1975
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 5 (6) , 403-408
- https://doi.org/10.1080/00397917508065572
Abstract
1,2-Disubstituted aziridines 2 are not readily accessible and most syntheses remain laborious3. We recently reported4 that reaction of α,α-dihalogenated aldimines with lithium aluminium hydride provided a facile synthesis of 1,1-disubstituted aziridines (a three step synthesis starting from ordinary aliphatic aldehydes).Keywords
This publication has 3 references indexed in Scilit:
- N‐2‐(1, 1‐Dichloroalkylidene) Cyclohexylamines. III1, 2Bulletin des Sociétés Chimiques Belges, 1975
- Alcaloides steroidiques CLXVIII Agrandissement de cycle par action de l'aluminohydrure de lithium sur une imine α-trihalogenee.Tetrahedron Letters, 1974
- Reduction of α-halogenated imines synthesis of pyrroles and aziridinesTetrahedron Letters, 1974