PROTECTION OF IMIDE GROUP OF URACIL MOIETY BY MEANS OF 2,2,2-TRICHLORO-TERT-BUTYLOXYCARBONYL CHLORIDE: A SELECTIVE SYNTHESIS OF 2′-O-METHYLURIDINE
- 5 July 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 11 (7) , 965-968
- https://doi.org/10.1246/cl.1982.965
Abstract
2,2,2-Trichloro-tert-butyloxycarbonyl group (TCBOC) was useful protecting group for the protection of imide function of uracil moiety. Starting from N3-TCBOC uridine derivative, 2′-O-methyluridine was selectively synthesized without formation of N3-methyluridine derivatives.Keywords
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