Hepatic processing of IgA: Studies using analytical and preparative subcellular fractionation
- 1 December 1981
- journal article
- research article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 1 (12) , 921-926
- https://doi.org/10.1007/bf01114961
Abstract
IgA uptake by rat liver was followed by a combination of perfusion and centrifugation techniques. Subcellular processing of IgA was complex, involving binding to plasma membranes, followed by translocation to at least 2 compartments of widely differing densities on sucrose gradients, neither of which appear to be lysosomal. Use of a labeled antibody to the plasma membrane enzyme 5''-nucleotidase indicated that only part of this activity was co-transported with IgA.This publication has 12 references indexed in Scilit:
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