Anti‐ss‐a antibody and other antinuclear antibodies in systemic lupus erythematosus

Abstract
Randomly selected sera from 88 patients with systemic lupus erythematosus (SLE) were studied for the frequency of antibodies to SS‐A, SS‐B, RANA, RNP, Sm, Sc‐1, and dsDNA. Results were in agreement with previous reports except for an increased incidence of anti‐SS‐A antibody (33%). Nine of 14 patients with anti‐SS‐A antibody on whom serial studies were performed had fluctuating titers. Titer changes often correlated with disease activity and dsDNA antibody levels.