Oxygen mass transfer into aerated CMC solutions in a bubble column

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Abstract
Differing findings on the volumetric mass transfer coefficients kLa in CMC solutions in bubble column bioreactors have been reported in the literature. Therefore, oxygen mass transfer was studied again in CMC solutions in a 14-cm-i.d. × 270-cm-height bubble column using different spargers. The kLa values were determined along with the dispersion coefficients by fitting the prediction of the axial dispersed plug model with the experimental oxygen concentration profiles in the liquid phase. Surprisingly, the obtained liquid phase dispersion coefficients for CMC solution are higher than one would expect from correlations. The kLa data depend largely on the flow regime. In general, they are lower than those reported in the literature. The data for developing slug and established slug flow are dependent on the gas velocity and the effective viscosity of the solution and can br correlated by a simple correlation. This correlation describes kLa values measured on fermentation broth of Penicillium chrysogenum with striking agreement.

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