Loss of Specific Antigenicity on Carboxymethylation of Mercaptoethanol-Reduced Interferon of Human Leukocyte Origin

1 January 1973

journal article
research article
Published by S. Karger AG in Intervirology

Vol. 2 (1) , 52-55
https://doi.org/10.1159/000149405

Abstract

Carboxymethylation of mercaptoethanol-reduced human leukocyte interferon (IF) destroyed its antiviral activity and antigenicity; both seem to be dependent upon the integrity of at least one disulfide bond.

Keywords

DISULFIDE BONDS
INTERFERON
LEUKOCYTES
LYMPHOCYTES

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