Sterile eosinophile Pustulose

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Abstract
‘Eosinophilic pustular folliculitis’, first described by Ofuji and co-workers in 1970, is obviously a new entity, not only confined to Japan. Recently, there was a case reported from Sweden; we present here the first observation in the FRG. The disease is characterized by eruptions of aggregated pustules, containing numerous eosinophils, and by blood eosinophilia. In our patient the disease first appeared on the scalp, leading to scarring alopecia. Since in our and in some other patients the lesions were not limited to the follicles, we feel that the term ‘sterile eosinophilic pustulosis’ is more appropriate to reflect the clinical picture. For differential diagnosis Morbus Duhring and M. Sneddon-Wilkinson have to be considered. ‘Sterile eosinophilic pustulosis’ differs from these mainly because of the eosinophilic infiltrations deep in the dermis. Immunofluorescence tests are negative. Treatment with DADPS may be helpful.

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