Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

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Abstract
The 9213-nucleotide structure of the AIDS[acquired immune deficiency syndrome]/lymphadenopathy virus was determined from molecular clones representing the integrated provirus and viral RNA. The virus is highly polymorphic and lacks significant nucleotide homology with type C retroviruses characterized previously. Together with an analysis of the 2 major viral subgenomic RNA, these studies establish the coding frames for the gag, pol and env genes and predict the expression of a novel gene at the 3'' end of the genome unrelated to the X genes of HTLV-I and -II.