Multidrug resistance and the role of P-glycoprotein knockout mice

This publication has 18 references indexed in Scilit:

• Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
  Published by Elsevier ,1994
• Clinical reversal of the multidrug resistance phenotype: True tumour modulation or pharmacokinetic interaction?
  European Journal Of Cancer, 1994
• BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER
  Annual Review of Biochemistry, 1993
• Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line
  Science, 1992
• P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma
  New England Journal of Medicine, 1991
• Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas.
  Molecular and Cellular Biology, 1990
• Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities.
  Molecular and Cellular Biology, 1990
• Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells
  Published by Elsevier ,1989
• The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.
  Molecular and Cellular Biology, 1989
• Expression of Multidrug Resistance Gene in Human Cancers
  JNCI Journal of the National Cancer Institute, 1989