Brief Communication: Susceptibility of an Inbred Strain of Guinea Pigs to the Induction of Pancreatic Adenocarcinoma by N-Methyl-N-nitrosourea2
- 1 March 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 52 (3) , 991-993
- https://doi.org/10.1093/jnci/52.3.991
Abstract
Adenocarcinoma of the pancreas developed by week 36 in 4 of 11 inbred strain-13 guinea pigs that survived weekly intragastric administration of 10 mg N-methyl-N-nitrosourea/kg body weight for >6 months. The short induction period suggests that this inbred strain of guinea pigs is valuable in developing a suitable biologic model for pancreatic adenocarcinoma.Keywords
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