Variations in Muscle Electrolyte Composition Due to Sampling and to Aging.

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Abstract
Variation in muscle electrolyte composition was tested by taking samples from the thigh and from the paravertebral muscles of 2 groups of normal rats aged 11 and 18 weeks respectively. The thigh muscle in each instance contained more chloride and less K than the back muscles when the data were expressed in terms of day fat-free solids. The difference in K was not observed when it was expressed as concentration in calculated intra-cellular water. It was postulated that the differences noted were due to differences in the connective tissue content of the 2 samples. A decrease in muscle K concentration with increasing age (11-18 weeks) was observed. It was noted that a reciprocal increase in muscle Na concentration occurred so that the sum of the 2 remained constant.

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