EPIDEMIC INFLUENZA: STUDIES IN CLINICAL EPIDEMIOLOGY

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Abstract
Clinical epidemiology represents a compromise between the purely statistical method of studying an epidemic and that of clinical investigation in which the individual patient is the unit. It applies the methods of clinical investigation to epidemics, thus gaining detailed information of a significant but not complete number of patients. This method has been employed in recent studies of epidemic influenza revealing that the disease is caused by a filterable virus; that serological tests can be used in diagnosis and in differentiating epidemic influenza from other respiratory diseases of somewhat similar symptomatology. It has revealed that relapses of influenza really represent complicating bacterial infections and that the sym-tomatology of the disease is relatively characteristic in contrast to the so-called febrile catarrhs.

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