Inhibition by Somatostatin of LH-RH-Induced LH Release in Normal Menstruating Women
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Gynecologic and Obstetric Investigation
- Vol. 22 (1) , 17-21
- https://doi.org/10.1159/000298884
Abstract
The present study was carried out in order to establish whether the concomitant treatment with somatostatin (SRIH) is capable of modifying gonadotrophin release in response to LH-RH administration in normal women during follicular, periovulatory, and luteal phases. SRIH was administered in a dose of 5.55 µg/min over 180 min and LH-RH (100 µg) was injected as a bolus at 90 min after the beginning of SRIH infusion. Within the dose used, SRIH significantly reduced LH response to LH-RH, whereas it did not alter FSH response to LH-RH. These results suggest that SRIH may play a part in the regulation of LH secretion in normal women.Keywords
This publication has 1 reference indexed in Scilit:
- Norepinephrine Levels in the Rat Hypothalamus During the Estrous CycleEndocrinology, 1967