Linkage of Genes Controlling the Rate of Synthesis and Structure of Aminolevulinate Dehydratase
- 24 September 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (4003) , 1245-1246
- https://doi.org/10.1126/science.173.4003.1245
Abstract
The rate of synthesis of δ-aminolevulinate dehydratase in mice is controlled by alleles at the levulinate ( Lv ) locus. Two structural mutations modifying the sensitivity of δ-aminolevulinate dehydratase to heat have been identified. Genetic analyses established that the structural locus for δ-aminolevulinate dehydratase was either physically close to or identical with the locus that controls its rate of synthesis.Keywords
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