EFFECT OF CASTRATION AND ANDROGENS ON BODY AND ORGAN WEIGHTS, AND THE ARGINASE AND PHOSPHATASES OF KIDNEY AND LIVER OF THE MALE SYRIAN HAMSTER

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Abstract
Castration caused a decrease in the size of the seminal vesicles and prostates but no change in the kidney or liver. The admn. of testosterone propionate by injn. or by the subcut. implantation of a pellet for 20 and 140 days increased the seminal vesicles and prostates of castrated hamsters to greater than normal but did hot affect the size of the kidney or liver. Pellets of testosterone and 17-methyltestosterone implanted subcut. for 20 days produced similar responses. The arginase of the kidney increased as a result of castration and decreased to normal with the various androgen treatments; the ''alkaline'' phosphatase decreased after castration and was restored to normal with androgen treatment. The ''acid'' phosphatase of the kidney and the arginase and phosphatases of the liver were not affected by castration or by the androgen treatment.