SINUSOIDAL FETAL HEART-RATE PATTERN ASSOCIATED WITH ALPHAPRODINE ADMINISTRATION

  • 1 January 1978
    • journal article
    • research article
    • Vol. 52  (6) , 678-681
Abstract
Sinusoidal fetal heart rate patterns were observed in 42.5% of 40 women who had received alphaprodine (Nisentil) for relief of labor pain. Analysis showed that the pattern appeared approximately 19 min following alphaprodine administration and persisted for approximately 60 min. In 18 patients [controls] who did not receive narcotic analgesia, an intermittent sinusoidal pattern was observed in 1 patient. All babies with sinusoidal heart rate during labor had 1 min Apgar scores of 7 or greater except 2 in the study group. Both these neonates had low Apgar scores directly associated with complications at delivery. All 5 min Apgar scores were 7 or greater, and there were no perinatal deaths.

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