Production of Luteoskyrin, a Hepatotoxic Pigment, by Penicillium islandicum Sopp
- 1 January 1969
- journal article
- research article
- Published by American Society for Microbiology in Applied Microbiology
- Vol. 18 (3) , 406-409
- https://doi.org/10.1128/aem.18.3.406-409.1969
Abstract
Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for preparation of 14C-labeled luteoskyrin was 2-14C-malonate.Keywords
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