Effects of Insulin and Activity on Pentose Transport Into Muscle

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Abstract
The effects of insulin and muscular activity on the transport across the cell membrane of muscle of pentoses having the same steric configuration about carbon atoms 1, 2 and 3 as d-glucose has, were found to be additive in the nephrectomized cat. The degree of intracellular penetration of l-arabinose into muscle was found to be related to the extent of activity. The results suggest that the effect of muscular activity on pentose penetration is not due to a humoral agent. They also suggest that insulin and muscular activity exert their effects by different mechanisms.