Effects of Age, Castration and/or Steroids upon Hematocrit in Male Rats.

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Abstract
The micro-method of Strumia, Sample and Hart was used to determine the hematocrit of rats in 12 groups: intact rats of different ages, rats castrated at different ages, intact and castrated rats injected with sesame oil (SO) alone, or with SO containing hormones, and castrated rats injected with water-soluble testosterone (17-B, diethylamino-ethyl-carbonate hydrochloride). Some results confirmed previous findings: hematocrits of rats castrated as adults were lower than those of intact animals; testosterone pro-pionate returned hematocrits to normal after castration, but did not cause elevation above normal in intact or castrated animals. Estradiol benzoate did not significantly lower hematocrits of intact and castrates. New findings: hematocrits of neonatally castrated rats were not significantly different from those of intact adults and thus differed from those of animals castrated as adults and examined 14 days later. Aqueous testosterone returned hematocrits of castrates to normal. There was a trend in both intact and castrates for sesame oil to increase the hematocrit.

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