Antiallergic activity of 4-hydroxy-3-nitrocoumarins

1 April 1975

journal article
Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry

Vol. 18 (4) , 391-394
https://doi.org/10.1021/jm00238a014

Abstract

Twenty-four substituted 4-hydroxy-3-nitrocoumarins have been prepared for nitration of the corresponding 4-hydroxycoumarins. All were found to possess antiallergic activity as measured by the homocytotropic antibody-antigen induced passive cutaneous anaphylaxis reaction in the rat.

Keywords

ANTIBODY
ANAPHYLAXIS
RAT
CUTANEOUS
ANTIGEN
SUBSTITUTED
HYDROXY
CORRESPONDING
TWENTY
NITROCOUMARINS

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