HYPERSENSITIVENESS TO PITUITARY EXTRACTS

15 February 1936

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 106 (7) , 512-515
https://doi.org/10.1001/jama.1936.02770070008003

Abstract

Hypersensitiveness to pituitary extract is apparently an uncommon condition. Hasson¹in 1930 reported a case of general reaction following the injection of pituitary extract, and Wang and Maxwell²in 1933 reported a similar case of shock which occurred post partum and which they proved, by reinjecting a smaller quantity of the drug, to be due to solution of posterior pituitary. In neither of these cases is there a record of skin tests or of other allergic studies. One of us³recently described a case, which is presented here with four others that came to our attention later. Personal inquiry⁴has revealed six other cases of general reaction in which posterior pituitary extract was suspected as the etiologic factor. In a period of less than two years five cases of hypersensitiveness to pituitary extract have been observed in the Louisville City Hospital, three of the cases occurring

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