Inhibitors of the cleavage of aclacinomycins
- 1 December 1987
- journal article
- Published by Springer Nature in Biotechnology Letters
- Vol. 9 (12) , 837-842
- https://doi.org/10.1007/bf01026192
Abstract
The reductive cleavage of the aclacinomycins A (I), Y (II), and B (III) by intact mycelia or subcellular fractions of the producer strain S. spec. AM 33352/F43 is suppressed in the presence of uncouplers, complex-forming agents, detergents, and some metal anions such as chromate. Increased concentration of the latter in complete cultures caused rearrangement of I to III.Keywords
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