Correlation of Hexokinase Content and Basal Energy Metabolism in Discrete Regions of Rat Brain
- 1 March 1986
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 46 (3) , 983-985
- https://doi.org/10.1111/j.1471-4159.1986.tb13066.x
Abstract
Brain hexokinase (ATP:D-hexose 6-phosphotransferase, EC 2.7.1.1) levels in seven regions of rat brain were estimated by photometric measurement of immunofluorescence in cryostat-cut sections. When compared with basal rates of glucose metabolism in these regions, estimated by the 6-[14C]glucose method, a significant correlation was observed. Thus, hexokinase content reflects metabolic energy demands.Keywords
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