Medullary Thyroid Cancer: The Functions of raf-1 and Human Achaete-scute Homologue-1
- 1 June 2005
- journal article
- review article
- Published by Mary Ann Liebert Inc in Thyroid®
- Vol. 15 (6) , 511-521
- https://doi.org/10.1089/thy.2005.15.511
Abstract
Medullary thyroid cancer (MTC) is a prototypic neuroendocrine tumor of the thyroid C cells. Other than surgery, there are no curative therapies for MTC. In this review, we detail recent studies that suggest that targeting specific signaling pathways may be a viable strategy to control MTC tumor progression. Specifically, we discuss the role of the raf-1 and achaete-scute homologue-1 pathways in the MTC tumor growth and differentiation.Keywords
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