The therapeutic potential of iron chelators
- 1 December 1999
- journal article
- Published by Informa Healthcare in Expert Opinion on Investigational Drugs
- Vol. 8 (12) , 2141-2158
- https://doi.org/10.1517/13543784.8.12.2141
Abstract
In recent years there has been much interest in the development of iron (Fe) chelators for treatment of a number of clinical conditions in addition to beta-thalassaemia. These include cancer, anthracycline-mediated cardiotoxicity, malaria, AIDS and the severe neurodegenerative disease, Friedreich's ataxia. In this review I will discuss the most recent advances achieved in the potential treatment of these conditions using Fe chelators.Keywords
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