Clomipramine versus Phenelzine in Obsessive–Compulsive Disorder
- 1 November 1992
- journal article
- clinical trial
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 161 (5) , 665-670
- https://doi.org/10.1192/bjp.161.5.665
Abstract
A double-blind clinical trial of clomipramine versus phenelzine was carried out on 30 patients suffering from DSM–III obsessive–compulsive disorder. The study period was 12 weeks, and the maximum doses used (from the fifth week on) were 225 mg/day for clomipramine (14 patients) and 75 mg/day for phenelzine (12 patients); four patients dropped out. Obsessive symptoms improved significantly in both drug groups, but there was no significant difference between groups. Depressive symptoms improved before obsessive ones.Keywords
This publication has 24 references indexed in Scilit:
- Clomipramine, Self-exposure and Therapist-aided Exposure for Obsessive–Compulsive RitualsThe British Journal of Psychiatry, 1988
- Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiologyBiological Psychiatry, 1987
- Obsessive-compulsive disorder and serotonin: Is there a connection?Biological Psychiatry, 1985
- Response to Tranylcypromine and Thought Stopping in Obsessional DisorderThe British Journal of Psychiatry, 1984
- Tricyclic Antidepressants in Obsessive-Compulsive Disorder Antiobsessional or Antidepressant Agents?Journal of Nervous & Mental Disease, 1983
- Clomipramine and Exposure for Obsessive-Compulsive Rituals: 1The British Journal of Psychiatry, 1980
- Angina pectoris among 10,000 menThe American Journal of Medicine, 1976
- A RATING SCALE FOR DEPRESSIONJournal of Neurology, Neurosurgery & Psychiatry, 1960
- THE ASSESSMENT OF ANXIETY STATES BY RATINGPsychology and Psychotherapy: Theory, Research and Practice, 1959