Creatinine in Serum and Plasma Direct Microdetermination by Kinetics
- 1 January 1972
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 5 (11) , 815-827
- https://doi.org/10.1080/00032717208069563
Abstract
A kinetic method for the determination of creatinine in 50 ul of serum or plasma, without deproteinization or pre-treatment, at rate of 50 to 100 samples an hour is described. The precision is better than 2% (CV) in the normal range and the recovery very close to 100%. The method is linear at least up to 10−3 M (11.3 mg/lOOml) and can be standardized with aqueous creatinine solutions. Glucose and proteins do not interfere with the reaction.Keywords
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