Pd(0)–PhCOOH catalyzed addition of oxygen pronucleophiles to allenes and internal alkynes
- 1 June 2005
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 83 (6-7) , 569-573
- https://doi.org/10.1139/v05-043
Abstract
We have developed a catalytic system that enables the addition of alcohols to allenes using a combination of 5 mol% Pd(PPh3)4 and 10 mol% benzoic acid. Likewise, the addition reaction of carboxylic acids to alkynes is described. In all cases the reaction proceeded well, giving the corresponding allylation products in good-to-high yields with high regio- and stereoselectivities.Key words: addition, alcohols, carboxylic acids, allenes, alkynes, palladium.Keywords
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