Dermatofibrosarcoma protuberans: a clinicopathological and immunohistochemical study with a review of the literature
- 1 September 1985
- journal article
- research article
- Published by Wiley in Histopathology
- Vol. 9 (9) , 921-938
- https://doi.org/10.1111/j.1365-2559.1985.tb02878.x
Abstract
Forty‐one cases of dermatofibrosarcoma protuberans are presented. The clinical features and histopathological appearances are described. Immunohistochemical staining of thirteen cases with antisera to lysozyme, α1‐antichymotrypsin and S‐100 protein has provided no evidence to support either a histiocytic or neuroectodermal origin for these tumours. In reviewing the literature, the histogenetic origin, differential diagnosis and malignant potential of dermatofibrosarcoma protuberans are discussed.Keywords
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