Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum

1 January 1976

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1

No. 11,p. 1165-1170
https://doi.org/10.1039/p19760001165

Abstract

The structure of compactin (I){7-[1,2,6,7,8,8a-hexahydro-2-methyl-8-(2-methylbutyryloxy)naphthyl]-3-hydroxyheptan-5-olide}, a metabolite isolated from cultures of Penicillium brevicompactum, has been determined by a combination of spectroscopic, chemical, and X-ray crystallographic methods.