Multiple genes forXenopusactivin receptor expressed during early embryogenesis
- 25 May 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 303 (1) , 81-84
- https://doi.org/10.1016/0014-5793(92)80482-v
Abstract
Four distinct cDNAs for activin receptor designated as XSTK2, 3, 8 and 9 have been cloned from a Xenopus laevis cDNA library. The protein structures deduced from the cDNAs have shown that they all have a putative extracellular ligand-binding domain, a single transmembrane domain and cytoplasmic Ser/Thr kinase domain, except that XSTK2 is extremely similar to the XSTK3 gene but lacks a carboxyl-terminal part of the kinase motif. Northern blot analysis showed that all transcripts are maternally inherited. The levels or transcript for XSTK2, 3 and 8 appeared to fluctuate during early development while those for XSTK9 maintain constant.Keywords
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