Protein synthesis by reticulocyte ribosomes, II. The effects of magnesium ion and chloramphenicol on induced protein synthesis.

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Abstract
There are many differences between poly U and natural template RNA with respect to their interaction with ribosomes, their effectiveness in the stimulation of protein synthesis under comparable conditions, and the susceptibility of the induced protein synthesis to inhibition by chloramphenicol. The differences observed between poly U and natural template RNA may be related to factors which affect the interaction of template RNA and ribosomes. Because of these differences, results obtained using synthetic template RNA may not necessarily reflect the role of natural template RNA in protein synthesis.