Glucose-6-Phosphate Dehydrogenase Activity in the Adrenal Cortex of the Sodium Depleted Rat: A Histochemical Study*

Publisher Website
Google Scholar
Abstract
Sodium deprivation in the adult white rat causes enlargement of the zona glomerulosa of the adrenal cortex. This enlargement is accomplished by the proliferation of small groups of cells in the immediate subcapsular area which are characterized by marked activity of G-6-P dehydrogenase and by low lipid content. This is in contrast to the cells of the inner portion of the zone, which like the cells of the normal glomerulosa, are poor in G-6-P dehydrogenase activity and relatively rich in lipids. These observations suggest that the glomerulosa of the rat is not homogeneous but is composed of at least 2 types of cells which differ biochemically in their response to sodium deprivation.

This publication has 0 references indexed in Scilit: